Full name:

ATPase, Ca++ transporting, type 2C, member 1

Synonyms:

HHD; BCPM; PMR1; SPCA1; hSPCA1; ATP2C1A

Swissprot:

P98194

Gene Accession:

BC028139

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.