Background:

This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

TPM4

Immunogen:

Fusion protein of human TPM4

Full name:

tropomyosin 4

Synonyms：

HEL-S-108

SwissProt:

P67936

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

10-50

WB Predicted band size:

29 kDa

WB Positive control:

Mouse brain tissue

WB Recommended dilution:

200-1000